pentobarbital will lower the extent or effect of linagliptin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Use of alternative treatments is strongly encouraged when linagliptin should be to be administered with a CYP3A4 inducer
pentobarbital will lessen the extent or result of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will minimize the level or impact of alfuzosin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unidentified.
pentobarbital will lessen the level or result of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Potent CYP3A4 inducers are anticipated to bring about sizeable decreases in sildenafil plasma ranges
pentobarbital will lower the extent or outcome of etravirine by influencing hepatic enzyme CYP2C9/ten metabolism. Use Warning/Observe.
Reserve concomitant prescribing of such drugs in patients for whom other cure selections are insufficient. Restrict dosages and durations into the bare minimum required. Check closely for signs of respiratory despair and sedation.
benzhydrocodone/acetaminophen and pentobarbital both improve sedation. Steer clear of or Use Alternate Drug. Restrict use to individuals for whom choice therapy selections are inadequate
pentobarbital will minimize the level or outcome of methadone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will reduce the level or effect of cyclosporine by influencing get more info hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will minimize the level or outcome of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Strong or reasonable CYP3A4 inducers might boost rate of diazepam elimination; hence, efficacy of diazepam could possibly be decreased.
pentobarbital will reduce the level or result of cinacalcet by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will decrease the extent or result of fludrocortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will lessen the level or impact of lumacaftor/ivacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
If inducer is discontinued, contemplate oliceridine dosage reduction and keep an eye on for signs of respiratory despair.